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Coordination Compounds of Cu(II), Ni(II) Based on Ethyl 4-benzoate Thiosemicarbazons Derivatives of Salicyl Aldehyde. Antimicrobial and Antifungal Properties
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| dc.contributor.author | RUSNAC, A. | |
| dc.contributor.author | BALAN, G. | |
| dc.contributor.author | GULEA, A. | |
| dc.date.accessioned | 2021-11-15T11:34:51Z | |
| dc.date.available | 2021-11-15T11:34:51Z | |
| dc.date.issued | 2021 | |
| dc.identifier.citation | RUSNAC, A., BALAN, G., GULEA, A. Coordination Compounds of Cu(II), Ni(II) Based on Ethyl 4-benzoate Thiosemicarbazons Derivatives of Salicyl Aldehyde. Antimicrobial and Antifungal Properties. In: ICNMBE-2021: the 5th International Conference on Nanotechnologies and Biomedical Engineering, November 3-5, 2021: Program and abstract book. Chişinău, 2021, p. 114. ISBN 978-9975-72-592-7. | en_US |
| dc.identifier.isbn | 978-9975-72-592-7 | |
| dc.identifier.uri | http://repository.utm.md/handle/5014/18054 | |
| dc.description | Only Abstract. | en_US |
| dc.description.abstract | The article publishes in vitro tests of the antibacterial and antifungal properties of new сoordination compounds of Cu(II), Ni(II) based on ethyl 4-benzoate thiosemicarbazons derivatives of salicyl aldehyde. Two Gram-positive strains were taken as reference strains: Staphylococcus aureus ATCC 25923 and Bacillus cereus ATCC 11778; two Gram-negative strains: E.coli ATCC 25922 and Acinetobacter baumannii BAA-747; three fungal strains: Candida albicans ATCC 10231, Candida krusei ATCC 6258, Cryptococcus neoformans CECT 1043. The best results were recorded at {Ni(HL1)Cl} complex, a selectivity is observed on Cryptococcus neoformans, with CMI = 0.016, CMF = 0.031 mg/mL and is twice as active as the control substance Nystatin. The purity and structural formula of synthesized compounds was confirmed by thin layer chromatography; IR spectroscopy; 1H, 13C Nuclear Magnetic Resonance Spectroscopy, metal analysis and magnetochemical analysis. | en_US |
| dc.language.iso | en | en_US |
| dc.publisher | Universitatea Tehnică a Moldovei | en_US |
| dc.rights | Attribution-NonCommercial-NoDerivs 3.0 United States | * |
| dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/3.0/us/ | * |
| dc.subject | compounds of Cu(II), Ni(II) | en_US |
| dc.subject | salicyl aldehyde | en_US |
| dc.subject | Nuclear Magnetic Resonance Spectroscopy | en_US |
| dc.title | Coordination Compounds of Cu(II), Ni(II) Based on Ethyl 4-benzoate Thiosemicarbazons Derivatives of Salicyl Aldehyde. Antimicrobial and Antifungal Properties | en_US |
| dc.type | Article | en_US |
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