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Peroxidation Kinetics involving the Complexes of Cytochrome c and Cardiolipin in the Presence of Lipid Antioxidants

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dc.contributor.author KANAROVSKII, E. Yu.
dc.contributor.author YALTYCHENKO, O.V.
dc.contributor.author GORINCHOY, N.N.
dc.date.accessioned 2020-12-07T17:29:33Z
dc.date.available 2020-12-07T17:29:33Z
dc.date.issued 2017
dc.identifier.citation KANAROVSKII, E. Yu., YALTYCHENKO, O.V., GORINCHOY, N.N. Peroxidation Kinetics involving the Complexes of Cytochrome c and Cardiolipin in the Presence of Lipid Antioxidants. In: Microelectronics and Computer Science: proc. of the 9th intern. conf., October 19-21, 2017. Chişinău, 2017, pp. 350-353. ISBN 978-9975-4264-8-0. en_US
dc.identifier.isbn 978-9975-4264-8-0
dc.identifier.uri http://repository.utm.md/handle/5014/11954
dc.description.abstract This paper represents a theoretical description of the kinetics, taking into account the mechanism of antiradical activity of the antioxidant. Based on the analysis of this problem, a kinetic model is formulated that includes two pathways in which the reactions characteristic of the lipid peroxidation process take place. The enzymatic pathway includes reactions involving the complex of cytochrome c and cardiolipin, and the non-enzymatic pathway is reactions involving the free lipid radicals. A system of differential equations describing the kinetics of the lipid peroxidation process is constructed both with and without the inhibiting effect of the antioxidant. Relying on the existing theoretical and experimental data, the considered kinetic model of the lipid peroxidation process can be used to study and compare the antiradical activity of various antioxidants, in particular vitamin E (α-tocopherol) and some of its homologues with the shortened side chains. en_US
dc.language.iso en en_US
dc.publisher Technical University of Moldova en_US
dc.rights Attribution-NonCommercial-NoDerivs 3.0 United States *
dc.rights.uri http://creativecommons.org/licenses/by-nc-nd/3.0/us/ *
dc.subject antioxidant en_US
dc.subject complex of cytochrome c–cardiolipin en_US
dc.subject free radicals en_US
dc.subject kinetics en_US
dc.subject lipid peroxidation en_US
dc.title Peroxidation Kinetics involving the Complexes of Cytochrome c and Cardiolipin in the Presence of Lipid Antioxidants en_US
dc.type Article en_US


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