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Smartphone-based Pupillometer with Chromatic Stimuli to Screen Neuro-ophthalmological Diseases

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dc.contributor.author SOUSA, A. I.
dc.contributor.author NEVES, C. M.
dc.contributor.author VIEIRA, P.
dc.date.accessioned 2021-11-12T12:01:19Z
dc.date.available 2021-11-12T12:01:19Z
dc.date.issued 2021
dc.identifier.citation SOUSA, A. I., NEVES, C. M., VIEIRA, P. Smartphone-based Pupillometer with Chromatic Stimuli to Screen Neuro-ophthalmological Diseases. In: ICNMBE-2021: the 5th International Conference on Nanotechnologies and Biomedical Engineering, November 3-5, 2021: Program and abstract book. Chişinău, 2021, p. 72. ISBN 978-9975-72-592-7. en_US
dc.identifier.isbn 978-9975-72-592-7
dc.identifier.uri http://repository.utm.md/handle/5014/18004
dc.description Only Abstract en_US
dc.description.abstract Pupillometry technique has gained an increased interest over the years as it allows to objectively assess patient’s consciousness and neuro-ophthalmological status by measuring pupillary light reflex (PLR). Chromatic pupillometry emerged with the discovery of intrinsically photosensitive retinal ganglion cells (ipRGCs), blue light sensitive and contributors to PLR. Automated pupillometers have been developed over the years to quantitatively measure PLR but have a reduced possibility to be a widespread screening tool as they are expensive and not portable. In this study, a smartphone-based pupillometer was developed, taking advantage of this technology accessibility, low-cost price, and portability. Chromatic stimuli were considered in this smartphone-based pupillometer to assess the contribution of ipRGCs to PLR and allow the screening of the neuro-ophthalmological diseases. In this preliminary study, six healthy individuals participated and pupillometric data was collected using the smartphone application developed, testing different protocols and background light conditions. The system presented good quality of eye images acquired and good behaviour in pupil data extraction. The acquisition protocols tested showed promising results to be used for chromatic pupillometry, although increasing the number of participants is mandatory and further research is needed. Nevertheless, this study shows the potential of the developed pupillometer to function as low cost, portable and accessible screening tool for neuroophthalmological diseases. en_US
dc.language.iso en en_US
dc.publisher Universitatea Tehnică a Moldovei en_US
dc.rights Attribution-NonCommercial-NoDerivs 3.0 United States *
dc.rights.uri http://creativecommons.org/licenses/by-nc-nd/3.0/us/ *
dc.subject intrinsically photosensitive retinal ganglion cells (ipRGCs) en_US
dc.subject pupillary light reflex (PLR) en_US
dc.subject automated pupillometers en_US
dc.subject.classification pupillary light reflex en_US
dc.title Smartphone-based Pupillometer with Chromatic Stimuli to Screen Neuro-ophthalmological Diseases en_US
dc.type Article en_US


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