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Assessment of Gold Nanoparticles Uptake in Tissues of Female Mice and Their Offspring Using Neutron Activation Analysis

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dc.contributor.author IVLIEVA, A.
dc.contributor.author ZINICOVSCAIA, I.
dc.contributor.author PETRITSKAYA, E.
dc.contributor.author YUSHIN, N.
dc.contributor.author ROGATKIN, D.
dc.contributor.author PESHKOVA, A.
dc.date.accessioned 2021-11-15T10:57:38Z
dc.date.available 2021-11-15T10:57:38Z
dc.date.issued 2021
dc.identifier.citation IVLIEVA, A., ZINICOVSCAIA, I., PETRITSKAYA, E. et al. Assessment of Gold Nanoparticles Uptake in Tissues of Female Mice and Their Offspring Using Neutron Activation Analysis. In: ICNMBE-2021: the 5th International Conference on Nanotechnologies and Biomedical Engineering, November 3-5, 2021: Program and abstract book. Chişinău, 2021, p. 91. ISBN 978-9975-72-592-7. en_US
dc.identifier.isbn 978-9975-72-592-7
dc.identifier.uri http://repository.utm.md/handle/5014/18045
dc.description Only Abstract en_US
dc.description.abstract The uptake of gold in different tissues of female mice and their offspring after prolonged oral administration of gold nanoparticles to the females during pregnancy and lactation was investigated. Gold content in different organs was determined using neutron activation analysis. The highest content of gold was accumulated in kidneys followed by liver, lungs, blood and brain. Accumulation of gold in brain confirms ability of nanoparticles to pass through placental and blood-brain barriers. The average specific mass content of gold which crossed the blood-brain barrier was 3.8 ng/g (for female) and 1.1 ng/g (for offspring). The results are important for research on developmental and reproductive toxicity and safety of nanomaterials. en_US
dc.language.iso en en_US
dc.publisher Universitatea Tehnică a Moldovei en_US
dc.rights Attribution-NonCommercial-NoDerivs 3.0 United States *
dc.rights.uri http://creativecommons.org/licenses/by-nc-nd/3.0/us/ *
dc.subject gold nanoparticles en_US
dc.subject neutron en_US
dc.subject reproductive and safety of nanomaterials en_US
dc.title Assessment of Gold Nanoparticles Uptake in Tissues of Female Mice and Their Offspring Using Neutron Activation Analysis en_US
dc.type Article en_US


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