2023: Recent submissions

  • In vivo Evaluation of PMMA Antiglaucoma Shunt’s Biocompatibility 
    IACUBITCHII, Maria; BENDELIC, Eugeniu; PADUCA, Ala; COCIUG, Adrian; GIRALDEZ FERNANDEZ, Maria Jesus (Springer Nature Switzerland, 2023)
    The histocompatibility of traditional trabeculectomy in comparison to PMMA antiglaucoma shunt with valve implant in the rabbit’s eyes. The preclinical research included the implantation of the newly designed PMMA antiglaucoma ...
  • Hemodynamic Protective Assessment of BurnNavi-Guided Fluid Management in Burned Patients: Pilot Study 
    MELNYCHENKO, Mykola; DMYTRIIEV, Dmytro; NAZARCHUK, Oleksandr; SIDORENKO, Ludmila; CHORNOPYSHCHUK, Roman; NAGAICHUK, Vasyl; SIDORENKO, Svetlana (Springer Nature Switzerland, 2023)
    Burn injuries remain a leading cause of mortality and morbidity worldwide. Many formulas have been described for burn resuscitation using various combinations, but there is still no consensus on the most effective method. ...
  • Personalised Medicine Implementation in Lowand Middle-Income Countries 
    GUSILA, Ilenuta; TOPA, Alexandra; ZARBAILOV, Natalia; LUNGU, Natalia; CUROCICHIN, Ghenadie (Springer Nature Switzerland, 2023)
    The potential of Personalised Medicine makes it attractive to health systems, and personalised approaches are being applied in practice in highly developed countries. However, the implementation of personalised medicine ...
  • Prospective, Descriptive Study of Rotaviral Infection in Vaccinated and Non-vaccinated Infants from Republic of Moldova 
    DONOS, Ala; ILIEV, Albina-Mihaela (Springer Nature Switzerland, 2023)
    Acute diarrheal disease is one of the most current health problems of the baby. Rotaviral infection is the most common cause of dehydration in infants and young children. The implementation of the sentinel surveillance of ...
  • The Prevalence of Allele Frequencies of CYP2C19 Polymorphisms of Clinically Important Drug-Metabolizing Enzymes CYP2C19 in Moldova Healthy Population 
    DOGOT, Marta; GALEA-ABDUSA, Daniela; BUZA, Anastasia; CUROCICHIN, Ghenadie; CAPROS, Natalia (Springer Nature Switzerland, 2023)
    Genetic polymorphisms of drug-metabolizing enzymes, such as cytochrome P450 oxidases, can alter the pharmacokinetic properties of administered drugs, leading to variability in drug responses. Prior knowledge of allele ...
  • Assessment of Oxidative Stress Markers in Obese Patients with Community-Acquired Pneumonia 
    DUMITRAS, Tatiana; FETCO-MEREUTA, Diana; CAPROS, Natalia; CHIHAI, Viorica; TERNA, Eudochia; MATCOVSCHI, Sergiu; CASCAVAL, Virginia (Springer Nature Switzerland, 2023)
    Obesity is associated with a low antioxidant defense compared with normal weight. Total antioxidant status is lower in obese than in normal weight adults, and this anti-oxidant imbalance favors systemic oxidative stress. ...
  • Updates on the Use of Ozone Therapy in Patients with COVID-19. A Review 
    CERNEI, Natalia; TROFIMOV, Cristina; GRABOVSCHI, Ion; BALTAGA, Ruslan; ARNAUT, Oleg (Springer Nature Switzerland, 2023)
    To date, there are no specific antiviral treatment strategies for COVID-19 patients. Empiric approaches used for other viral infections wasn’t effective against SARS-CoV-2. Thus, some urgent therapeutic alternatives are ...
  • The Peculiarities of Circadian Rhythms and Their Implications on Parkinson’s Disease 
    ROTARU, Lilia; CEBUC, Mădălina; LUPUŞOR, Adrian; GROSU, Oxana; VOVC, Victor; LOZOVANU, Svetlana; CĂRĂUŞUL, Ghenadie; GROPPA, Stanislav (Springer Nature Switzerland, 2023)
    Unsettling epidemiological data suggest Parkinson’s disease as the second most common neurodegenerative disorder worldwide. The worries persist as there is a demographic tendency towards the ageing of the population as the ...
  • Combined and Complex Treatment-Optimal Therapies in Rectal Cancer 
    UNGUREANU, Cezara; GHIDIRIM, Nicolae (Springer Nature Switzerland, 2023)
    Despite advances in medicine and national screening there is a continuous increase in the incidence of rectal cancer. Surgical treatment remained the mainstay of treatment, but neoadjuvant therapy has demonstrated in recent ...
  • Improvement of Cardiovascular System Diseases Diagnostics by Using Multiparametric Data 
    SHYSHKIN, Mykhailo; HOLDOBIN, Serhii; BUTOVA, Olha (Springer Nature Switzerland, 2023)
    The most common cause of death among humans is cardiovascular disease. An effective way to detect early signs of cardiovascular disease is to constantly monitor the patient's critical physiological parameters during their ...
  • Diagnosing Pulmonary Embolism with Computed Tomography Pulmonary Angiography 
    RANGA, Doina; CAPROS, Natalia; CEALAN, Andrei; SIRBU, Ion; TALMACI, Cornelia; MATCOVSCHI, Sergiu (Springer Nature Switzerland, 2023)
    Pulmonary embolism (PE) is the third most common cause of cardiovascular mortality after myocardial infarction and stroke. Incidence rates range from 53 to 162 per 100 000 inhabitants. The CTPA is reported as the standard ...
  • Synergy Effect of Ascorbic Acid and α-Tocopherol in Kinetic Model of Lipid Peroxidation 
    KANAROVSKII, Evghenii; YALTYCHENKO, Olga (Springer Nature Switzerland, 2023)
    The synergy effect of α-tocopherol and ascorbic acid (vitamins E and C) is taken into account in the presented theoretical model of the kinetics of the process of lipid peroxidation (LPO). An analysis of the features in ...
  • Method for Increasing the Production or Activity of Catalase in the Body 
    ANDRONACHE, Lilia; PANTEA, Valeriana; CEBAN, Emil; GULEA, Aurelian; GRAUR, Vasilii; ŢAPCOV, Victor; MATCOVSCHII, Valerii; GUDUMAC, Valentin (Springer Nature Switzerland, 2023)
    The aim of this study is to develop a new, more sensitive and accurate method for the induction and/or activation of catalase (CAT) in the body. The proposed goal is achieved by using bromo-2-{[2-(prop-2-en-1-ylcarbamoth ...
  • Non Conventional Methods in Visual Function Training for Children with Sight Disabilities 
    BRAUN, Barbu-Cristian; DRUGĂ, Cornelui-Nicolae; ŞERBAN, Ionel; MITU, Leonard (Springer Nature Switzerland, 2023)
    The paper presents a new unconventional method, complementary to the classic ones, by which, through the tablet or laptop, children with different visual impairments can be assisted in the recovery process through assisted ...
  • Thiol-Disulfide Homeostasis in Kidney Tumors in Children 
    BERNIC, Jana; CIUNTU, Angela; HANGANU, Elena; ROLLER, Victor; PETROVICI, Vergil; BĂLUTEL, Tatiana; GUDUMAC, Eva (Springer Nature Switzerland, 2023)
    Renal tumors in children occupy the 4th place, succumbing to hemoblastomas, tumors of the central nervous system and lymphomas, and constitute 5.5–7.0% of all malignant tumors in children. Emphasis on the severity of renal ...
  • The Implementation of Personalized Medicine in the Republic of Moldova: Challenges and Opportunities in Cardiology 
    LEVITCHI, Alexei; GALEA-ABDUSA, Daniela; SONTEA, Victor; CUROCICHIN, Ghenadie (Springer Nature Switzerland, 2023)
    Implementing Personalized Medicine in the operational and functional context of a healthcare system is a complex challenge for most countries. Pharmacogenetics represents the application domain of individual genetic profile ...
  • Assessing the Impact of Parental Labor Migration on Children’s Health 
    GORBUNOV, Galina (Springer Nature Switzerland, 2023)
    In the Republic of Moldova, the phenomenon of children separated from one or both parents who went abroad to work has reached one of the highest levels in Europe. A total of 36,817 children were affected by parental labor ...
  • Role of Botulinum Toxin a Injections as a Salvage Therapy for Refractory Overactive Bladder: Insights from Urodynamic Studies 
    IVANOV, Mihaela; CEBAN, Emil (Springer Nature Switzerland, 2023)
    The aim of study was to establish the role of botulinum toxin A (BTX-A) in the treatment of refractory idiopathic overactive bladder (OAB) patients and to find out if urodynamic values could predict the positive third line ...
  • Modern Methods for Identification and Reduction of Visual Problems in Children 
    BRAUN, Barbu-Cristian; DRUGĂ, Corneliu-Nicolae; ŞERBAN, Ionel; TULICĂ, Alexandru (Springer Nature Switzerland, 2023)
    The paper presents a stage of research done in order to help optometrists in the pediatric field. This stage of the research focused in particular on the development of a new solution regarding, first of all, the screening ...
  • Unsupervised Knowledge Extraction from Biomedical Data 
    BASARAB, Matei; VLAICU, Petru Alexandru; ROGOVSCHI, Nicoleta; GROZAVU, Nistor (Springer Nature Switzerland, 2023)
    In this paper we introduce a study on the use of the unsupervised representation learning on biomedical data i.e. on Growth weight data and Wisconsin Diagnostic Breast Cancer obtaining good performances in terms of clustering ...

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