The Critical Size Bone Defects - In-Vivo Experimental Method of the Treatment with the Decellularized Vascularized Bone Allografts

Abstract

The work aims to study the local and paraclinical postoperative manifestations after the plasty of the critical bone defect with vascularized bone allotransplantation in the rabbit model METHODS: The 12 rabbits (New Zealand White Rabbits) were divided into three groups, weighing 2.6–4.6 kg. Lot 1 - plasty of critical bone defects with vascularized bone autograft. Lot 2 - plasty of critical bone defects with native vascularized bone allograft. Lot 3 - plasty of critical bone defects with decellularized vascularized bone allograft. We have studied the local (on the 1st, 5th, 10th, and 15th postoperative days) and the paraclinical postoperative manifestations (at 14 and 30 days postoperatively) after the lateral intermuscular and the medial approach of the thigh.