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The Sentinel Surveillance System of Severe Acute Respiratory Infections Associated with Influenza in Children from Republic of Moldova

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dc.contributor.author DONOS, Ala
dc.contributor.author ILIEV, Albina-Mihaela
dc.date.accessioned 2023-11-10T08:45:33Z
dc.date.available 2023-11-10T08:45:33Z
dc.date.issued 2023
dc.identifier.citation DONOS, Ala, ILIEV, Albina-Mihaela. The Sentinel Surveillance System of Severe Acute Respiratory Infections Associated with Influenza in Children from Republic of Moldova. In: 6th International Conference on Nanotechnologies and Biomedical Engineering: proc. of ICNBME-2023, 20–23, 2023, Chisinau, vol. 1: Nanotechnologies and Nano-biomaterials for Applications in Medicine, 2023, p. 554-563. ISBN 978-3-031-42774-9. e-ISBN 978-3-031-42775-6. en_US
dc.identifier.isbn 978-3-031-42774-9
dc.identifier.isbn 978-3-031-42775-6
dc.identifier.uri https://doi.org/10.1007/978-3-031-42775-6_59
dc.identifier.uri http://repository.utm.md/handle/5014/24750
dc.description Acces full text - https://doi.org/10.1007/978-3-031-42775-6_59 en_US
dc.description.abstract Acute respiratory pathology has the highest incidence in children, the most vulnerable are still those aged up to 5 years. Extremely difficult are the cases with severe acute respiratory infections (SARI), manifested by pneumonia and bronchopneumonia associated with influenza. Essential method used is the sentinel epidemiological surveillance; molecular biology techniques in real time (rRT-PCR) to detect viruses in biological material (nasopharyngeal exudates); isolation of influenza viruses in cell cultures MDCK and MDCK-SIAT1 after WHO methodology; identification by the hemagglutination inhibition test with reference antisera for influenza A(H1N1) pdm09, A(H3N2) and B, provided by the WHO Collaborating Centre, National Institute of Health Researches (London, UK). Thus, it was found that SARI associated with the flu threatens the health and life of children, with a major risk in children aged between 0–4 years. In conclusion, the obtained results show, that the identification and evaluation of phenotypic, genotypic and antigenic properties of the influenza viruses, have a major importance, in the context of fairness policy, for the use of influenza vaccine in compulsory seasonal immunization of the children, optimizing the management of treatment and prophylaxis of influenza, including in combination with SARI, foreseeing epidemic process and reducing the negatively impact on the health system. en_US
dc.language.iso en en_US
dc.publisher Springer Nature Switzerland en_US
dc.rights Attribution-NonCommercial-NoDerivs 3.0 United States *
dc.rights.uri http://creativecommons.org/licenses/by-nc-nd/3.0/us/ *
dc.subject childrens respiratory infections en_US
dc.subject influenza virus en_US
dc.subject surveillance en_US
dc.subject epidemic seasons en_US
dc.subject viruses en_US
dc.title The Sentinel Surveillance System of Severe Acute Respiratory Infections Associated with Influenza in Children from Republic of Moldova en_US
dc.type Article en_US


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  • 2023
    6th International Conference on Nanotechnologies and Biomedical Engineering, September 20–23, 2023, Chisinau, Moldova

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Attribution-NonCommercial-NoDerivs 3.0 United States Except where otherwise noted, this item's license is described as Attribution-NonCommercial-NoDerivs 3.0 United States

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