Environmental, Activity-dependent Modulation of Theta Rhythm During REM Sleep by its Selective Deprivation and Subsequent rebound

Abstract

The work is aimed at experimental testing of the possibility of an activity-dependent increase in power and representation of theta rhythm (4-8Hz) in REM sleep episodes. Polysomnography was performed in mature male rat (n=20) by means of electroencephalogram, electrohippocampogram, electrooculogram, electromyogram (EEG)/EHpG/EOG/EMG) leads using “Spike4” software (Cambridge Electronic Design) and was combined with video behavior monitoring. Recordings were repeated three times: baseline, selective REM sleep deprivation, and post-deprivation recovery sleep during daylight hours (08:00 am–06:00 pm).