Modulation of the gut - brain axis using psychobiotics in neurodegenerative diseases

Abstract

One of microbiome research's most challenging and divisive issues is the link between gut microbial metabolism and mental health. Understanding the therapeutic impact of gut bacteria on mental health is of utmost importance for increasing the well-being state of the world's population. Psychobiotics are a type of probiotic that influence central nervous system processes and human behaviors via neural, immune, and metabolic pathways regulated by the gut - brain axis. They increase not only gastrointestinal function but also antidepressant and anxiolytic ability