Abstract:
Actinobacteria (actinomycetes) are in the center of attention because these bacteria produce a variety of natural drugs and other biologically active metabolites, including: antibiotics, enzymes, inhibitors. The strain Saccharopolyspora spinosa DSM-44228 was used for the experiments. Cultivation was carried out in the initial stages on agar medium and then moved to deep cultivation on liquid medium. We have been able to achieve good growth and sporulation over 7 days on agar medium. On liquid medium we have developed two compositions on which there was a good accumulation of biomass, but they have not yet been determined the amount of produced Spinosad. We are going to carry out the optimization of the medium to achieve a maximum possible production of biomass.
Description:
Research was carried out within the project of the State Program 20.80009.7007.04 “Biotechnologies and genetical processes for evaluation, conservation and exploitation of agrobiodiversity”, financed by the National Agency for Research and Development. We thank Leibniz Institute, DSMZ-German Collection of Microorganisms and Cell Cultures GmbH for granting S. spinosa strain DSM 44228.
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