Prevalence of some PIK3CA mutations in patients with cervical Squamous Carcinoma from the Republic of Moldova

Abstract

The study aimed to determine the prevalence of mutations in the PIK3CA gene in a cohort of CSCC patients from the Republic of Moldova. The tested prevalence of the PIK3CA mutations was 29.35%. Testing revealed that 25 patients were positive for a single mutation, and two tested positive for a double mutation. Since many patients have these mutations, there is a chance that CSCC patients from the Republic of Moldova will benefit from the development of anti-PI3K targeted therapy.