DSpace Repository

Medicines based on nanosized silica – achievements and prospects

Show simple item record

dc.contributor.author GERASHCHENKO, Igor
dc.date.accessioned 2024-04-25T12:27:43Z
dc.date.available 2024-04-25T12:27:43Z
dc.date.issued 2024
dc.identifier.citation GERASHCHENKO, Igor. Medicines based on nanosized silica – achievements and prospects. In: Quo Vadis – Ethics of the Scientific Research: conf. NANO-2024, event devoted to the 60th anniversary of the Technical University of Moldova, 15-18 April 2024, Chişinău, Republica Moldova: Program and proceedings of the conference, Chişinău 2024, pp. 79-81. ISBN 978-9975-64-422-8. en_US
dc.identifier.isbn 978-9975-64-422-8
dc.identifier.uri http://repository.utm.md/handle/5014/26923
dc.description.abstract Nanosized (highly dispersed, fumed) silica obtained by the vapor phase process has an extremely wide application in various areas of industrial activity. Its physicochemical characteristics, including adsorption capacity, have been well examined [1]. In pharmaceuticals, fumed silica has long been used as an effective and safe excipient in the manufacture of tablets, ointments, liniments and other dosage forms. A real innovation was the use of fumed silica as an independent medicine with sorption action. The credit for this belongs to the Ukrainian team of chemists, pharmacists and doctors [2]. The effectiveness of fumed silica as an enterosorbent is based primarily on its extraordinary ability to bind proteins, such as microbial and food toxins. Fumed silica is also considered as an enveloping agent that interacts with the glycoproteins of the intestinal mucosa, forming a barrier for the absorption of toxic substances and preventing the adhesion of pathogenic microorganisms [3]. The peak of studying the medical and biological properties of nanosized fumed silica has already passed; today, enterosorbents based on it, for example Polysorb plus, Atoxil®, Carbowhite®, are in stable demand on the Ukrainian market. en_US
dc.language.iso en en_US
dc.publisher Technical University of Moldova en_US
dc.relation.ispartofseries NANO-2024 "Quo Vadis – Ethics of the Scientific Research", event devoted to the 60th anniversary of the Technical University of Moldova;15-18 April 2024, Chişinău, Republica Moldova
dc.rights Attribution-NonCommercial-NoDerivs 3.0 United States *
dc.rights.uri http://creativecommons.org/licenses/by-nc-nd/3.0/us/ *
dc.subject nanosized silica en_US
dc.subject enterosorbent en_US
dc.subject treatment of wounds en_US
dc.title Medicines based on nanosized silica – achievements and prospects en_US
dc.type Article en_US


Files in this item

The following license files are associated with this item:

This item appears in the following Collection(s)

Show simple item record

Attribution-NonCommercial-NoDerivs 3.0 United States Except where otherwise noted, this item's license is described as Attribution-NonCommercial-NoDerivs 3.0 United States

Search DSpace


Advanced Search

Browse

My Account