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Self-propelled nanotools drilling into cells and tissues

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dc.contributor.author SANCHEZ, Samuel
dc.contributor.author XI, Wang
dc.contributor.author SOLOVEV, Alexander
dc.contributor.author SCHMIDT, Oliver
dc.date.accessioned 2019-10-25T09:27:58Z
dc.date.available 2019-10-25T09:27:58Z
dc.date.issued 2013
dc.identifier.citation SANCHEZ, Samuel, XI, Wang, SOLOVEV, Alexander, SCHMIDT, Oliver. Self-propelled nanotools drilling into cells and tissues. In: ICNBME-2013. International Conference on Nanotechnologies and Biomedical Engineering. German-Moldovan Workshop on Novel Nanomaterials for Electronic, Photonic and Biomedical Applications: proc. of the 2th intern. conf., April 18-20, 2013. Chişinău, 2013, pp. 426-428. ISBN 978-9975-62-343-8. en_US
dc.identifier.isbn 978-9975-62-343-8
dc.identifier.uri http://repository.utm.md/handle/5014/5268
dc.description.abstract We designed nanoscale tools in the form of autonomous and remotely guided catalytically and magnetically self-propelled micro- and nanotools. Asymmetrically rolled-up nanotools move in a corkscrewlike trajectory, allowing these tiny tubes to drill and embed themselves into biomaterials (fixed HeLa cells and tissues). First, we designed the smallest self-propelled nanojet engine (InGaAs/GaAs/(Cr)Pt) with diameters in the range of 280–600 nm, which move in hydrogen peroxide solutions with speeds as high as 180 μm.s-1 and perform advanced tasks such as drilling into cancer cells. Also, we demonstrated that tubular fuelfree Ti/Cr/Fe micro-drillers containing sharp tips can be applied for mechanical drilling operations of porcine liver tissue ex vivo. An external rotational magnetic field is used to remotely locate and actuate the micro-drillers in a solution with a viscosity comparable to that of biological fluids (e.g., blood). en_US
dc.language.iso en en_US
dc.publisher Tehnica UTM en_US
dc.rights Attribution-NonCommercial-NoDerivs 3.0 United States *
dc.rights.uri http://creativecommons.org/licenses/by-nc-nd/3.0/us/ *
dc.subject nanotools en_US
dc.subject nanojet engine en_US
dc.subject remotely controlled en_US
dc.subject rolled-up nanotechnology en_US
dc.title Self-propelled nanotools drilling into cells and tissues en_US
dc.type Article en_US


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