Simulation of speckle structure of scattered light inside multi-layered skin tissue

Abstract

Calculation results on speckle patterns formed by multiply scattered light in multi-layered biological tissue are given. They are obtained by using the earlier-designed analytical procedure that is based on the engineering methods for solving to the radiative transfer equation and the relations between the coherence theory and the theory of light propagation through a scattering medium. The given examples illustrate the opportunities of the procedure. A special part of the paper is devoted to the inverse problems of biomedical optics that can be posed and solved by the designed procedure. In particular, there is shown the sensitivity of the contrast of the interference patterns formed by multiply scattered light to blood volume fraction and blood oxygen saturation.