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Copper-Containing Polyoxometalates: Syntheses and Anticancer Activity against the SH-SY5Y Human Neuroblastoma Cell Line

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dc.contributor.author GUTUL, T.
dc.contributor.author DIMOGLO, A.
dc.contributor.author MIRONIC, T.
dc.date.accessioned 2020-05-15T13:28:23Z
dc.date.available 2020-05-15T13:28:23Z
dc.date.issued 2015
dc.identifier.citation GUTUL, T., DIMOGLO, A., MIRONIC, T. Copper-Containing Polyoxometalates: Syntheses and Anticancer Activity against the SH-SY5Y Human Neuroblastoma Cell Line. In: ICNMBE: International conference on Nanotechnologies and Biomedical Engineering: proc. of the 3rd intern. conf., Sept. 23-26 : Program & Abstract Book , 2015. Chişinău, 2015, p. 86. en_US
dc.identifier.uri https://doi.org/10.1007/978-981-287-736-9_71
dc.identifier.uri http://repository.utm.md/handle/5014/8227
dc.description Access full text - https://doi.org/10.1007/978-981-287-736-9_71 en_US
dc.description.abstract A new method for synthesising new copper-containing polyoxometalates based on selenium and tungsten has been developed. The structure of one of the complexes has been decoded; the cytotoxic effect of the complex on the human neuroblastoma SH- SY5Y has been studied. The cell lines have been cultured at different concentrations of polyoxometalates in a DME medium for 24 h; the percentage of cell viability has been evaluated by 3-(4,5 dimethyl thiazol-2yl)-2,5 diphenyltetrazolium bromide and neutral red. Polyoxometalates have shown the dose dependent inhibition of cell proliferation. These results suggest that the polyoxometalates exhibit strong anticancer and apoptosis activity against human neuroblastoma SH-SY5Y cell line. en_US
dc.language.iso en en_US
dc.publisher Tehnica UTM en_US
dc.rights Attribution-NonCommercial-NoDerivs 3.0 United States *
dc.rights.uri http://creativecommons.org/licenses/by-nc-nd/3.0/us/ *
dc.subject polyoxometalates en_US
dc.subject cell lines en_US
dc.title Copper-Containing Polyoxometalates: Syntheses and Anticancer Activity against the SH-SY5Y Human Neuroblastoma Cell Line en_US
dc.type Article en_US


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