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Evaluation of the Quercetin Semisynthetic Derivatives Interaction with ABCG2 and Cyclooxygenase-2

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dc.contributor.author MANUKYAN, A. E.
dc.date.accessioned 2020-05-29T08:52:31Z
dc.date.available 2020-05-29T08:52:31Z
dc.date.issued 2019
dc.identifier.citation MANUKYAN, A. E. Evaluation of the Quercetin Semisynthetic Derivatives Interaction with ABCG2 and Cyclooxygenase-2. In: ICNMBE: International conference on Nanotechnologies and Biomedical Engineering: proc. of the 4rd intern. conf., Sept. 18-21 : Program & Abstract Book , 2019. Chişinău, 2019, p. 131. ISBN 978-9975-72-392-3. en_US
dc.identifier.isbn 978-9975-72-392-3
dc.identifier.uri https://doi.org/10.1007/978-3-030-31866-6_98
dc.identifier.uri http://repository.utm.md/handle/5014/8448
dc.description Access full text - https://doi.org/10.1007/978-3-030-31866-6_98 en_US
dc.description.abstract Cancer multiple drug resistance and the inflammatory process are the main problems for successful chemotherapy. In anticancer therapy, plant and semisynthetic compounds are considered as potential modifiers for ABCG2 and COX2 inhibitors. As a result of experiments carried out in silico, the possible interaction of ABCG2 and inhibition of COX-2 by semisynthetic derivatives of quercetin were first revealed. The physicochemical parameters of the studied lig- ands were revealed, after which, for reliability, they were compared with in vitro experiments. en_US
dc.language.iso en en_US
dc.publisher Tehnica UTM en_US
dc.rights Attribution-NonCommercial-NoDerivs 3.0 United States *
dc.rights.uri http://creativecommons.org/licenses/by-nc-nd/3.0/us/ *
dc.subject quercetin derivatives en_US
dc.subject anticancer therapy en_US
dc.title Evaluation of the Quercetin Semisynthetic Derivatives Interaction with ABCG2 and Cyclooxygenase-2 en_US
dc.type Article en_US


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