DSpace Repository

Mode of Artemisinins’ Action on Oxidative Stress, Genomic and G-quadruplex DNA

Show simple item record

dc.contributor.author GINOSYAN, S. G.
dc.contributor.author CHILINGARYAN, G. V.
dc.contributor.author GRABSKI, H. V.
dc.contributor.author GHULIKYAN, L. A.
dc.contributor.author AYVAZYAN, N. M.
dc.contributor.author TIRATSUYAN, S. G.
dc.date.accessioned 2020-05-29T10:24:30Z
dc.date.available 2020-05-29T10:24:30Z
dc.date.issued 2019
dc.identifier.citation GINOSYAN, G., CHILINGARYAN, G. V., GRABSKI, H. V. et al. Mode of Artemisinins’ Action on Oxidative Stress, Genomic and G-quadruplex DNA. In: ICNMBE: International conference on Nanotechnologies and Biomedical Engineering: proc. of the 4rd intern. conf., Sept. 18-21 : Program & Abstract Book , 2019. Chişinău, 2019, p. 135. ISBN 978-9975-72-392-3. en_US
dc.identifier.isbn 978-9975-72-392-3
dc.identifier.uri https://doi.org/10.1007/978-3-030-31866-6_97
dc.identifier.uri http://repository.utm.md/handle/5014/8455
dc.description Access full text - https://doi.org/10.1007/978-3-030-31866-6_97 en_US
dc.description.abstract The present study was conducted to evaluate the effect of artemisinins’ on the level of lipid peroxidation (LPO), spontaneous chemiluminescence of the S-180 sarcoma homogenate and to study the nature of the interaction with canonical and non-canonical forms of DNA. Artemisinins are secondary metabolites of the medicinal plant Artemisia annua have anti-inflammatory, anticarcinogenic, immunomodulatory, antimicrobial, antihelminthic, antiviral, antioxidant and other properties. Our preliminary reverse virtual screening demonstrated that the ligand-binding domain of the human glucocorticoid receptor is the optimal target for artemisinin as well as for dexamethasone. en_US
dc.language.iso en en_US
dc.publisher Tehnica UTM en_US
dc.rights Attribution-NonCommercial-NoDerivs 3.0 United States *
dc.rights.uri http://creativecommons.org/licenses/by-nc-nd/3.0/us/ *
dc.subject artemisinins en_US
dc.subject lipid peroxidation en_US
dc.subject chemiluminescence en_US
dc.subject sarcoma en_US
dc.title Mode of Artemisinins’ Action on Oxidative Stress, Genomic and G-quadruplex DNA en_US
dc.type Article en_US


Files in this item

The following license files are associated with this item:

This item appears in the following Collection(s)

Show simple item record

Attribution-NonCommercial-NoDerivs 3.0 United States Except where otherwise noted, this item's license is described as Attribution-NonCommercial-NoDerivs 3.0 United States

Search DSpace


Advanced Search

Browse

My Account