Динамика восстановления нейротрофики кожи после обработки раны конечности животного криогеном

Abstract

The skin’s injury of the hoof’s intermanual partition in cattle is followed very often by the appearance of persistent wounds which require a long treatment. During this research, the wound of the intermanual partition skin of an experienced animal was reproduced and then cleansed with liquid nitrogen. The regeneration of nervous fibers was studied using neurohistological methods. In five days one can observe the growth of the axons and the migration of peripheral glial cells on remained perineural covers from the nervous bundles of the derma to the granulations tissue and to recycling epidermis. In ten days the reparative histogenesis continues to increase. In the nervous trunks of the derma and in the nervous bundles of a superficial plexus on the border with epidermis, we can observe the appearance of thin myelinized fibers and the axons with flasks and bulbs rising on the ends. In fifteen days the bundles unmyelinated fibers, departing from the core nervous plexus, together with the blood vessels are penetrating in the high papillae cutis. On the twentieth day there is the wound healing: structural integrity of epidermis layers and the derma skin are restored. Processes of growth and myelinization of the axons come to the end, mature myelinization and non myelinization nervous fibers are formed. The presence of mature nervous fibers and nervous terminations in papillae cutis testify that to the given date neurotrophic functions of the skin tissues of the foot were restored